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zinbwave

This is the development version of zinbwave; for the stable release version, see zinbwave.

All Bioconductor versions of zinbwave

3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6

Zero-Inflated Negative Binomial Model for RNA-Seq Data

Bioconductor version: 3.24 · Package version: 1.35.0

Implements a general and flexible zero-inflated negative binomial model that can be used to provide a low-dimensional representations of single-cell RNA-seq data. The model accounts for zero inflation (dropouts), over-dispersion, and the count nature of the data. The model also accounts for the difference in library sizes and optionally for batch effects and/or other covariates, avoiding the need for pre-normalize the data.

Author: Davide Risso [aut, cre, cph], Svetlana Gribkova [aut], Fanny Perraudeau [aut], Jean-Philippe Vert [aut], Clara Bagatin [aut]

Maintainer: Davide Risso <risso.davide at gmail.com>

DOI: 10.18129/B9.bioc.zinbwave

Citation

From within R, enter citation("zinbwave"):

Davide Risso, Svetlana Gribkova, Fanny Perraudeau, Jean-Philippe Vert, Clara Bagatin. zinbwave: Zero-Inflated Negative Binomial Model for RNA-Seq Data. doi:10.18129/B9.bioc.zinbwave, R package version 1.35.0, https://bioconductor.org/packages/zinbwave.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("zinbwave")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version1.35.0
LicenseArtistic-2.0
Bug Reportshttps://github.com/drisso/zinbwave/issues
Last updated2026-04-28
In Bioconductor sinceBioC 3.6 (R-3.4) (8 years)
Downloads rank280 of 2,456
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsDimensionReduction, GeneExpression, ImmunoOncology, RNASeq, Sequencing, SingleCell, Software, Transcriptomics
Package Short Url https://bioconductor.org/packages/zinbwave/

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("zinbwave")
An introduction to ZINB-WaVE HTML R Script
Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packagezinbwave_1.35.0.tar.gz
Windows binary (x86_64)zinbwave_1.35.0.zip
macOS binary (arm64)zinbwave_1.35.0.tgz
macOS binary (x86_64)zinbwave_1.35.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/zinbwave
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/zinbwave
Package Downloads ReportDownload Stats
Dependencies

Depends: R (>= 3.4), methods, SummarizedExperiment, SingleCellExperiment

Imports: BiocParallel, softImpute, stats, genefilter, edgeR, Matrix

Suggests: knitr, rmarkdown, testthat, matrixStats, magrittr, scRNAseq, ggplot2, biomaRt, BiocStyle, Rtsne, DESeq2, sparseMatrixStats

Reverse dependencies

Imports Me (4): benchdamic, clusterExperiment, scBFA, singleCellTK

Suggests Me (2): MAST, splatter