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immReferent

This is the released version of immReferent; for the devel version, see immReferent.

An Interface for Immune Receptor and HLA Gene Reference Data


Bioconductor version: Release (3.23)

Provides a consistent interface for downloading, storing, and accessing immune receptor (TCR/BCR) and HLA sequences from IMGT, IPD-IMGT/HLA, and OGRDB (AIRR-C). Supports export to popular analysis tools including MiXCR, TRUST4, Cell Ranger, and IgBLAST. This package serves as a core dependency for immunogenomics packages, ensuring reliable and high-quality sequence access with local caching for reproducibility.

Author: Nick Borcherding [aut, cre]

Maintainer: Nick Borcherding <ncborch at gmail.com>

Citation (from within R, enter citation("immReferent")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("immReferent")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("immReferent")
Caching and Offline Usage of Reference Sets (IMGT & OGRDB) HTML R Script
Getting Started with immReferent HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews Annotation, Sequencing, Software
Version 1.0.0
In Bioconductor since BioC 3.23 (R-4.6) (< 6 months)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports Biostrings, httr, jsonlite, methods, rvest, tibble, yaml
System Requirements
URL https://github.com/BorchLab/immReferent/
Bug Reports https://github.com/BorchLab/immReferent/issues
See More
Suggests BiocManager, BiocStyle, knitr, mockery, spelling, rmarkdown, testthat (>= 3.0.0), withr
Linking To
Enhances
Depends On Me
Imports Me immApex
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package immReferent_1.0.0.tar.gz
Windows Binary (x86_64) immReferent_1.0.0.zip
macOS Binary (big-sur-x86_64) immReferent_1.0.0.tgz
macOS Binary (sonoma-arm64) immReferent_1.0.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/immReferent
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/immReferent
Bioc Package Browser https://code.bioconductor.org/browse/immReferent/
Package Short Url https://bioconductor.org/packages/immReferent/
Package Downloads Report Download Stats