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linkSet

This is the released version of linkSet; for the devel version, see linkSet.

All versions 3.24 (devel), 3.23 (release), 3.22

Base Classes for Storing Genomic Link Data


Bioconductor version: Release (3.23)

Provides a comprehensive framework for representing, analyzing, and visualizing genomic interactions, particularly focusing on gene-enhancer relationships. The package extends the GenomicRanges infrastructure to handle paired genomic regions with specialized methods for chromatin interaction data from Hi-C, Promoter Capture Hi-C (PCHi-C), and single-cell ATAC-seq experiments. Key features include conversion from common interaction formats, annotation of promoters and enhancers, distance-based analyses, interaction strength metrics, statistical modeling using CHiCANE methodology, and tailored visualization tools. The package aims to standardize the representation of genomic interaction data while providing domain-specific functions not available in general genomic interaction packages.

Author: Gilbert Han [aut, cre] ORCID iD ORCID: 0009-0000-0293-2467

Maintainer: Gilbert Han <GilbertHan1011 at gmail.com>

Citation (from within R, enter citation("linkSet")):

Gilbert Han. linkSet: Base Classes for Storing Genomic Link Data. doi:10.18129/B9.bioc.linkSet, R package version 1.2.0, https://bioconductor.org/packages/linkSet.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("linkSet")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

No vignettes available
Reference ManualPDF

Details

biocViews Coverage, DataRepresentation, HiC, Sequencing, SingleCell, Software
Version1.2.0
In Bioconductor sinceBioC 3.22 (R-4.5) (1 year)
License MIT + file LICENSE
Depends GenomicRanges, S4Vectors, R (>= 4.5.0)
Imports methods, IRanges, GenomeInfoDb, BiocGenerics, Organism.dplyr, InteractionSet, ggplot2, patchwork, scales, foreach, iterators, stats, rlang, MASS, data.table, DBI, doParallel, AnnotationDbi
System Requirements
URLhttps://github.com/GilbertHan1011/linkSet https://gilberthan1011.github.io/linkSet
Bug Reportshttps://github.com/GilbertHan1011/linkSet/issues/new
See More
Suggests knitr, rmarkdown, testthat, TxDb.Mmusculus.UCSC.mm10.knownGene, TxDb.Hsapiens.UCSC.hg38.knownGene, TxDb.Hsapiens.UCSC.hg19.knownGene, org.Mm.eg.db, org.Hs.eg.db, GenomicFeatures, GenomicInteractions, gamlss, gamlss.tr, BiocStyle, rtracklayer
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64) linkSet_1.2.0.zip
macOS Binary (big-sur-x86_64) linkSet_1.2.0.tgz
macOS Binary (sonoma-arm64) linkSet_1.2.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/linkSet
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/linkSet
Package Short Url https://bioconductor.org/packages/linkSet/
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