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A DownStream Chemo-Proteomics Analysis Pipeline

Bioconductor version: Release (3.19)

Doscheda focuses on quantitative chemoproteomics used to determine protein interaction profiles of small molecules from whole cell or tissue lysates using Mass Spectrometry data. The package provides a shiny application to run the pipeline, several visualisations and a downloadable report of an experiment.

Author: Bruno Contrino, Piero Ricchiuto

Maintainer: Bruno Contrino <br1contrino at>

Citation (from within R, enter citation("Doscheda")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

Doscheda HTML R Script
Reference Manual PDF


biocViews DataImport, MassSpectrometry, Normalization, Preprocessing, Proteomics, QualityControl, Regression, Software
Version 1.26.0
In Bioconductor since BioC 3.6 (R-3.4) (6.5 years)
License GPL-3
Depends R (>= 3.4)
Imports methods, drc, stats, httr, jsonlite, reshape2, vsn, affy, limma, stringr, ggplot2, graphics, grDevices, calibrate, corrgram, gridExtra, DT, shiny, shinydashboard, readxl, prodlim, matrixStats
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Suggests BiocStyle, knitr, rmarkdown, testthat
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Follow Installation instructions to use this package in your R session.

Source Package Doscheda_1.26.0.tar.gz
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macOS Binary (x86_64) Doscheda_1.26.0.tgz
macOS Binary (arm64) Doscheda_1.26.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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