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Gene Set Regulation (GS-Reg)

Bioconductor version: Release (3.19)

A package for gene set analysis based on the variability of expressions as well as a method to detect Alternative Splicing Events . It implements DIfferential RAnk Conservation (DIRAC) and gene set Expression Variation Analysis (EVA) methods. For detecting Differentially Spliced genes, it provides an implementation of the Spliced-EVA (SEVA).

Author: Bahman Afsari <bahman at>, Elana J. Fertig <ejfertig at>

Maintainer: Bahman Afsari <bahman at>, Elana J. Fertig <ejfertig at>

Citation (from within R, enter citation("GSReg")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

Working with the GSReg package PDF R Script
Reference Manual PDF


biocViews AlternativeSplicing, GeneExpression, GeneRegulation, GeneSetEnrichment, GeneticVariability, Pathways, Software
Version 1.38.0
In Bioconductor since BioC 3.0 (R-3.1) (10 years)
License GPL-2
Depends R (>= 2.13.1), Homo.sapiens,, GenomicFeatures, AnnotationDbi
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Suggests GenomicRanges, GSBenchMark
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Follow Installation instructions to use this package in your R session.

Source Package GSReg_1.38.0.tar.gz
Windows Binary
macOS Binary (x86_64) GSReg_1.38.0.tgz
macOS Binary (arm64) GSReg_1.38.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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