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epiSeeker

This is the released version of epiSeeker; for the devel version, see epiSeeker.

All versions 3.24 (devel), 3.23 (release)

epiSeeker: an R package for Annotation, Comparison and Visualization of multi-omics epigenetic data


Bioconductor version: Release (3.23)

This package implements functions to analyze multi-omics epigenetic data. Data of fragment type and base type are supported by epiSeeker. It provides functions to retrieve the nearest genes around the peak, annotate genomic region of the peak, statistical methods to estimate the significance of overlap among peak data sets, and motif analysis. It incorporates the GEO database for users to compare their own dataset with those deposited in the database. The comparison can be used to infer cooperative regulation and thus can be used to generate hypotheses. Several visualization functions are implemented to summarize the coverage of the peak experiment, average profile and heatmap of peaks binding to TSS regions, genomic annotation, distance to TSS, overlap of peaks or genes, and the single-base resolution epigenetic data by considering the strand, motif, and additional information.

Author: Guangchuang Yu [aut, cre, fnd] ORCID iD ORCID: 0000-0002-6485-8781 , Ming Li [ctb], Qianwen Wang [ctb], Yun Yan [ctb], Hervé Pagès [ctb], Michael Kluge [ctb], Thomas Schwarzl [ctb], Zhougeng Xu [ctb], Chun-Hui Gao [ctb]

Maintainer: Guangchuang Yu <guangchuangyu at gmail.com>

Citation (from within R, enter citation("epiSeeker")):

Guangchuang Yu. epiSeeker: epiSeeker: an R package for Annotation, Comparison and Visualization of multi-omics epigenetic data. doi:10.18129/B9.bioc.epiSeeker, R package version 1.0.0, https://bioconductor.org/packages/epiSeeker.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("epiSeeker")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("epiSeeker")
epiSeeker: an R package for Annotation, Comparison and Visualization of multi-omics epigenetic data HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews Annotation, ChIPSeq, Coverage, GeneRegulation, MotifAnnotation, MultipleComparison, Software, Visualization
Version1.0.0
In Bioconductor sinceBioC 3.23 (R-4.6) (< 6 months)
License Artistic-2.0
Depends R (>= 4.5.0)
Imports AnnotationDbi, aplot, bsseq, BiocGenerics, Biostrings, boot, dplyr, enrichplot, IRanges, GenomeInfoDb, GenomicRanges, GenomicFeatures, ggplot2, graphics, grDevices, magrittr, methods, plotrix, parallel, RColorBrewer, rlang, RSQLite, rtracklayer, S4Vectors, scales, stats, SummarizedExperiment, tibble, tidyselect, tidyr, utils, yulab.utils (>= 0.2.0), grid
System Requirements
URLhttps://github.com/YuLab-SMU/epiSeeker
Bug Reportshttps://github.com/YuLab-SMU/epiSeeker/issues
See More
Suggests ape, BSgenome, BSgenome.Hsapiens.UCSC.hg38, clusterProfiler, data.table, GEOmetadb, GEOquery, gggenes, ggimage, ggiraph, ggplotify, ggtree, gginnards, gridBase, gtools, ggupset, ggVennDiagram, JASPAR2024, knitr, org.Hs.eg.db, prettydoc, ReactomePA, rmarkdown, testthat, TFBSTools, TxDb.Hsapiens.UCSC.hg38.knownGene, universalmotif
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package epiSeeker_1.0.0.tar.gz
Windows Binary (x86_64) epiSeeker_1.0.0.zip (64-bit only)
macOS Binary (big-sur-x86_64) epiSeeker_1.0.0.tgz
macOS Binary (sonoma-arm64) epiSeeker_1.0.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/epiSeeker
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/epiSeeker
Package Short Url https://bioconductor.org/packages/epiSeeker/
Package Downloads ReportDownload Stats