Bioconductor Developer Survey 2026 Now Open!

methylclock

This is the released version of methylclock; for the devel version, see methylclock.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14

Methylclock - DNA methylation-based clocks


Bioconductor version: Release (3.23)

This package allows to estimate chronological and gestational DNA methylation (DNAm) age as well as biological age using different methylation clocks. Chronological DNAm age (in years) : Horvath's clock, Hannum's clock, BNN, Horvath's skin+blood clock, PedBE clock and Wu's clock. Gestational DNAm age : Knight's clock, Bohlin's clock, Mayne's clock and Lee's clocks. Biological DNAm clocks : Levine's clock and Telomere Length's clock.

Author: Dolors Pelegri-Siso [aut, cre] ORCID iD ORCID: 0000-0002-5993-3003 , Juan R. Gonzalez [aut] ORCID iD ORCID: 0000-0003-3267-2146

Maintainer: Dolors Pelegri-Siso <dolors.pelegri at isglobal.org>

Citation (from within R, enter citation("methylclock")):

Dolors Pelegri-Siso, Juan R. Gonzalez. methylclock: Methylclock - DNA methylation-based clocks. doi:10.18129/B9.bioc.methylclock, R package version 1.18.0, https://bioconductor.org/packages/methylclock.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("methylclock")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("methylclock")
DNAm age using diffrent methylation clocks HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews BiologicalQuestion, DNAMethylation, Normalization, Preprocessing, Software, StatisticalMethod
Version1.18.0
In Bioconductor sinceBioC 3.14 (R-4.1) (5 years)
License MIT + file LICENSE
Depends R (>= 4.1.0), methylclockData, devtools, quadprog
Imports Rcpp (>= 1.0.6), ExperimentHub, dplyr, impute, PerformanceAnalytics, Biobase, ggpmisc, tidyverse, ggplot2, ggpubr, minfi, tibble, RPMM, stats, graphics, tidyr, gridExtra, preprocessCore, dynamicTreeCut, planet
System Requirements
URLhttps://github.com/isglobal-brge/methylclock
Bug Reportshttps://github.com/isglobal-brge/methylclock/issues
See More
Suggests BiocStyle, knitr, GEOquery, rmarkdown
Linking To Rcpp
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package methylclock_1.18.0.tar.gz
Windows Binary (x86_64) methylclock_1.18.0.zip
macOS Binary (big-sur-x86_64) methylclock_1.18.0.tgz
macOS Binary (sonoma-arm64) methylclock_1.18.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/methylclock
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/methylclock
Package Short Url https://bioconductor.org/packages/methylclock/
Package Downloads ReportDownload Stats