An R package to uncover high-resolution protein-DNA interactions in ChIP-exo replicates

Bioconductor version: Release (2.14)

Strand specific peak-pair calling in ChIP-exo replicates. The cumulative Skellam distribution function (package 'skellam') is used to detect significant normalized count differences of opposed sign at each DNA strand (peak-pairs). Irreproducible discovery rate for overlapping peak-pairs across biological replicates is estimated using the package 'idr'.

Author: Pedro Madrigal <pm12 at sanger.ac.uk>

Maintainer: Pedro Madrigal <pm12 at sanger.ac.uk>

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PDF R Script CexoR Vignette
PDF   Reference Manual


biocViews Genetics, Sequencing, Software, Transcription
Version 1.2.0
In Bioconductor since BioC 2.13 (R-3.0)
License Artistic-2.0 | GPL-2 + file LICENSE
Depends R (>= 2.10.0), IRanges
Imports Rsamtools, GenomicRanges, rtracklayer, idr
Suggests RUnit, BiocGenerics, BiocStyle
System Requirements
Depends On Me
Imports Me
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Package Source CexoR_1.2.0.tar.gz
Windows Binary CexoR_1.2.0.zip (32- & 64-bit)
Mac OS X 10.6 (Snow Leopard) CexoR_1.2.0.tgz
Mac OS X 10.9 (Mavericks)
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