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This is the development version of katdetectr; for the stable release version, see katdetectr.

Detection, Characterization and Visualization of Kataegis in Sequencing Data

Bioconductor version: Development (3.20)

Kataegis refers to the occurrence of regional hypermutation and is a phenomenon observed in a wide range of malignancies. Using changepoint detection katdetectr aims to identify putative kataegis foci from common data-formats housing genomic variants. Katdetectr has shown to be a robust package for the detection, characterization and visualization of kataegis.

Author: Daan Hazelaar [aut, cre] , Job van Riet [aut] , Harmen van de Werken [ths]

Maintainer: Daan Hazelaar <daanhazelaar at>

Citation (from within R, enter citation("katdetectr")):


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if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


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Overview_katdetectr HTML R Script
Reference Manual PDF


biocViews Classification, SNP, Sequencing, Software, VariantAnnotation, WholeGenome
Version 1.7.0
In Bioconductor since BioC 3.16 (R-4.2) (1.5 years)
License GPL-3 + file LICENSE
Depends R (>= 4.2)
Imports Biobase(>= 2.54.0), BiocParallel(>= 1.26.2), BSgenome(>= 1.62.0), BSgenome.Hsapiens.UCSC.hg19(>= 1.4.3), BSgenome.Hsapiens.UCSC.hg38(>= 1.4.4), changepoint (>= 2.2.3), (>= 1.0.3), checkmate (>= 2.0.0), dplyr (>= 1.0.8), GenomeInfoDb(>= 1.28.4), GenomicRanges(>= 1.44.0), ggplot2 (>= 3.3.5), ggtext (>= 0.1.1), IRanges(>= 2.26.0), maftools(>= 2.10.5), methods (>= 4.1.3), plyranges(>= 1.17.0), Rdpack (>= 2.3.1), rlang (>= 1.0.2), S4Vectors(>= 0.30.2), scales (>= 1.2.0), tibble (>= 3.1.6), tidyr (>= 1.2.0), tools, utils, VariantAnnotation(>= 1.38.0)
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