eisaR
This is the released version of eisaR; for the devel version, see eisaR.
Exon-Intron Split Analysis (EISA) in R
Bioconductor version: Release (3.23)
Exon-intron split analysis (EISA) uses ordinary RNA-seq data to measure changes in mature RNA and pre-mRNA reads across different experimental conditions to quantify transcriptional and post-transcriptional regulation of gene expression. For details see Gaidatzis et al., Nat Biotechnol 2015. doi: 10.1038/nbt.3269. eisaR implements the major steps of EISA in R.
Author: Michael Stadler [aut, cre], Dimos Gaidatzis [aut], Lukas Burger [aut], Charlotte Soneson [aut]
Maintainer: Michael Stadler <michael.stadler at fmi.ch>
citation("eisaR")):
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.
Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.
Installation
To install this package, start R (version "4.6") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("eisaR")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("eisaR")| Generating reference files for spliced and unspliced abundance estimation with alignment-free methods | HTML | R Script |
| Using eisaR for Exon-Intron Split Analysis (EISA) | HTML | R Script |
| Reference Manual | ||
| NEWS | Text |
Details
| biocViews | FunctionalGenomics, GeneExpression, GeneRegulation, RNASeq, Regression, Software, Transcription, Transcriptomics |
| Version | 1.24.0 |
| In Bioconductor since | BioC 3.11 (R-4.0) (6.5 years) |
| License | GPL-3 |
| Depends | R (>= 4.1) |
| Imports | graphics, stats, GenomicRanges, S4Vectors, IRanges, limma, edgeR(>= 4.0), methods, SummarizedExperiment, BiocGenerics, utils |
| System Requirements | |
| URL | https://github.com/fmicompbio/eisaR |
| Bug Reports | https://github.com/fmicompbio/eisaR/issues |
See More
| Suggests | knitr, rmarkdown, testthat, BiocStyle, QuasR, Rbowtie, Rhisat2, Biostrings, BSgenome, BSgenome.Hsapiens.UCSC.hg38, ensembldb, AnnotationDbi, GenomicFeatures, txdbmaker, rtracklayer, withr |
| Linking To | |
| Enhances | |
| Depends On Me | |
| Imports Me | |
| Suggests Me | |
| Links To Me | |
| Build Report | Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | eisaR_1.24.0.tar.gz |
| Windows Binary (x86_64) | eisaR_1.24.0.zip |
| macOS Binary (big-sur-x86_64) | eisaR_1.24.0.tgz |
| macOS Binary (sonoma-arm64) | eisaR_1.24.0.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/eisaR |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/eisaR |
| Bioc Package Browser | https://code.bioconductor.org/browse/eisaR/ |
| Package Short Url | https://bioconductor.org/packages/eisaR/ |
| Package Downloads Report | Download Stats |