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epidecodeR

This is the released version of epidecodeR; for the devel version, see epidecodeR.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13

epidecodeR: a functional exploration tool for epigenetic and epitranscriptomic regulation


Bioconductor version: Release (3.23)

epidecodeR is a package capable of analysing impact of degree of DNA/RNA epigenetic chemical modifications on dysregulation of genes or proteins. This package integrates chemical modification data generated from a host of epigenomic or epitranscriptomic techniques such as ChIP-seq, ATAC-seq, m6A-seq, etc. and dysregulated gene lists in the form of differential gene expression, ribosome occupancy or differential protein translation and identify impact of dysregulation of genes caused due to varying degrees of chemical modifications associated with the genes. epidecodeR generates cumulative distribution function (CDF) plots showing shifts in trend of overall log2FC between genes divided into groups based on the degree of modification associated with the genes. The tool also tests for significance of difference in log2FC between groups of genes.

Author: Kandarp Joshi [aut, cre], Dan Ohtan Wang [aut]

Maintainer: Kandarp Joshi <kandarpbioinfo at gmail.com>

Citation (from within R, enter citation("epidecodeR")):

Kandarp Joshi, Dan Ohtan Wang. epidecodeR: epidecodeR: a functional exploration tool for epigenetic and epitranscriptomic regulation. doi:10.18129/B9.bioc.epidecodeR, R package version 1.20.0, https://bioconductor.org/packages/epidecodeR.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("epidecodeR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("epidecodeR")
epidecodeR: a functional exploration tool for epigenetic and epitranscriptomic regulation HTML R Script
Reference ManualPDF

Details

biocViews ChipOnChip, DifferentialExpression, Epigenetics, Epitranscriptomics, FunctionalGenomics, FunctionalPrediction, GeneExpression, GeneRegulation, HistoneModification, Software, SystemsBiology, Transcription, Transcriptomics
Version1.20.0
In Bioconductor sinceBioC 3.13 (R-4.1) (5.5 years)
License GPL-3
Depends R (>= 3.1.0)
Imports EnvStats, ggplot2, rtracklayer, GenomicRanges, IRanges, rstatix, ggpubr, methods, stats, utils, dplyr
System Requirements
URLhttps://github.com/kandarpRJ/epidecodeR https://epidecoder.shinyapps.io/shinyapp
Bug Reportshttps://github.com/kandarpRJ/epidecodeR/issues
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package epidecodeR_1.20.0.tar.gz
Windows Binary (x86_64) epidecodeR_1.20.0.zip (64-bit only)
macOS Binary (big-sur-x86_64) epidecodeR_1.20.0.tgz
macOS Binary (sonoma-arm64) epidecodeR_1.20.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/epidecodeR
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/epidecodeR
Package Short Url https://bioconductor.org/packages/epidecodeR/
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