Processing and analyzing bisulfite sequencing data

Bioconductor version: Development (3.0)

The BiSeq package provides useful classes and functions to handle and analyze targeted bisulfite sequencing (BS) data such as reduced-representation bisulfite sequencing (RRBS) data. In particular, it implements an algorithm to detect differentially methylated regions (DMRs). The package takes already aligned BS data from one or multiple samples.

Author: Katja Hebestreit, Hans-Ulrich Klein

Maintainer: Katja Hebestreit <katjah at>

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PDF R Script An Introduction to BiSeq
PDF   Reference Manual


biocViews DNAMethylation, Genetics, MethylSeq, Sequencing, Software
Version 1.5.3
In Bioconductor since BioC 2.12 (R-3.0)
License LGPL-3
Depends R (>= 2.15.2), methods, IRanges(>= 1.17.24), GenomicRanges, Formula
Imports methods, BiocGenerics, Biobase, IRanges, GenomicRanges, rtracklayer, parallel, betareg, lokern, Formula, globaltest
System Requirements
Depends On Me
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Package Source BiSeq_1.5.3.tar.gz
Windows Binary (32- & 64-bit)
Mac OS X 10.6 (Snow Leopard) BiSeq_1.5.3.tgz
Mac OS X 10.9 (Mavericks)
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