To install this package, start R and enter:

## try http:// if https:// URLs are not supported

In most cases, you don't need to download the package archive at all.




This is the development version of pRoloc; for the stable release version, see pRoloc.

A unifying bioinformatics framework for spatial proteomics

Bioconductor version: Development (3.5)

This package implements pattern recognition techniques on quantitiative mass spectrometry data to infer protein sub-cellular localisation.

Author: Laurent Gatto and Lisa M. Breckels with contributions from Thomas Burger and Samuel Wieczorek

Maintainer: Laurent Gatto <lg390 at>

Citation (from within R, enter citation("pRoloc")):


To install this package, start R and enter:

## try http:// if https:// URLs are not supported


To view documentation for the version of this package installed in your system, start R and enter:



PDF R Script A transfer learning algorithm for spatial proteomics
PDF R Script HUPO 2011 poster: pRoloc -- A unifying bioinformatics framework for organelle proteomics
PDF R Script HUPO 2014 poster: A state-of-the-art machine learning pipeline for the analysis of spatial proteomics data
PDF Machine learning techniques available in pRoloc
PDF pRoloc tutorial
HTML R Script Annotating spatial proteomics data
PDF   Reference Manual
Text   NEWS
Video   pRoloc, pRolocdata and pRolocGUI


biocViews Classification, Clustering, MassSpectrometry, Proteomics, QualityControl, Software
Version 1.15.0
In Bioconductor since BioC 2.12 (R-3.0) (3.5 years)
License GPL-2
Depends R (>= 2.15), MSnbase(>= 1.19.20), MLInterfaces(>= 1.37.1), methods, Rcpp (>= 0.10.3), BiocParallel
Imports Biobase, mclust (>= 4.3), caret, e1071, sampling, class, kernlab, lattice, nnet, randomForest, proxy, FNN, BiocGenerics, stats, dendextend, RColorBrewer, scales, MASS, knitr, mvtnorm, gtools, plyr, ggplot2, biomaRt, utils, grDevices, graphics
LinkingTo Rcpp, RcppArmadillo
Suggests testthat, rmarkdown, pRolocdata (>= 1.9.4), roxygen2, synapter, xtable, tsne, hexbin, rgl, BiocStyle, hpar(>= 1.15.3), dplyr, GO.db, AnnotationDbi
Depends On Me pRolocGUI
Imports Me
Suggests Me MSnbase
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Package Source pRoloc_1.15.0.tar.gz
Windows Binary (32- & 64-bit)
Mac OS X 10.9 (Mavericks)
Subversion source (username/password: readonly)
Git source
Package Short Url
Package Downloads Report Download Stats

Documentation »


R / CRAN packages and documentation

Support »

Please read the posting guide. Post questions about Bioconductor to one of the following locations: